False positives on diagnostic tests for CHD.

False positives on diagnostic tests for CHD.

acceleration occurs at the time of valve closure, apparently as a result of the narrowing of the orifice in the face of this forward flow. In contrast, aortic valve closure occurs after cessation of forward flow in aortic stenosis,8 and hence no acceleration and no resulting augmentation of the murmur would be expected. Although the editorial raised a number of other points, with which we disag...

Controlling the proportion of false positives in multiple dependent tests.

Genome scan mapping experiments involve multiple tests of significance. Thus, controlling the error rate in such experiments is important. Simple extension of classical concepts results in attempts to control the genomewise error rate (GWER), i.e., the probability of even a single false positive among all tests. This results in very stringent comparisonwise error rates (CWER) and, consequently,...

Improbability Filtering for Rejecting False Positives

In this paper we describe a novel approach, called improbability filtering, to rejecting false-positive observations from degrading the tracking performance of an Extended Kalman-Bucy fdter. False-positives, incorrect observations reported with a high confidence, are a form of non-Gaussian white noise and therefore degrade the tracking performance of an Extended Kalman-Bucy Filter. Improbabilit...

False positives in cancer epidemiology.

BACKGROUND A recent attempt to estimate the false-positive rate for cancer epidemiology studies is based on agents in International Agency for Research on Cancer (IARC) category 3 (agent not classifiable as to its carcinogenicity to humans) in the IARC Monographs Program. METHODS The estimation method is critiqued regarding biases caused by its reliance on the IARC classification criteria for...

Minimizing false positives in differential display.